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Bone Marrow Transplantation
Bone Marrow Transplant in Turkey
A bone marrow transplant is a surgical procedure used to replace bone marrow that has been destroyed or damaged by chemotherapy, infection, or illness. This operation involves transferring blood undifferentiated organisms, which then enter deep down into the marrow to generate new blood cells while also promoting the formation of new marrow. Bone marrow transplant is called “autologous transplant” when the patient’s immature microorganisms conduct it, and “allogeneic transplant” when family members or irrelevant providers with tissue resemblance do it. Bone marrow transplants include the transfer of blood stem cells.
The soft, fat layer inside your bones is called bone marrow. It creates these blood components:
- Supplements of red blood cells distributed throughout the body
- White platelets that fight illness
- Platelets that assemble clumps
In addition, the bone marrow includes immature blood-forming stem cells that are known as hematopoietic stem cells, abbreviated as HSCs. The majority of cells are currently distinct from one another and have the ability to replicate themselves. These fundamental microorganisms are not specialized in any way, which means that they have the potential to multiply through the process of cell division and either continue to exist as undifferentiated organisms or diverge and evolve into a broad variety of platelet types. Your HSC, which is situated in your bone marrow, will continue to produce new blood cells for the rest of your life expectancy.
A bone marrow transplant replaces your damaged immature germs with healthy cells. This helps your body produce enough white, platelet, and red blood cells to prevent infections, bleeding, and anemia.
Stem cells that are in good health can come either from the body of a donor or from the patient. In these kinds of situations, it may be possible to collect or grow immature cells before beginning chemotherapy or radiation treatment. After that, the healthy cells are saved and preserved for later use in transplanting.
Why is Bone Marrow Transplant performed?
Bone Marrow Transplants are done when a person’s marrow isn’t healthy enough to function properly. This may be the result of long-term illnesses, cancer treatments, or infections. A transplant of bone marrow may be performed for several reasons, including reproducing the severely wounded basic microorganisms following shaft treatment and chemotherapy, which kills harmful cells in the body; lymphoma, leukemias, and sickle cell anemia which is a blood disorder that deforms red blood cells.
Types of Bone Marrow Transplant in Turkey
There are various types of bone marrow transplants. The two primary types are:
1. Autologous Transplant
In this type, your own body provides the undifferentiated cells needed for an autologous transplant. Radiation therapy or high-dose, intense chemotherapy can be utilized to treat cancer. Treatments like these can damage your immune system and stem cells. Because of this, before beginning cancer treatment, specialists will remove or salvage any undifferentiated organisms that may be present in your blood or bone marrow.
Following chemotherapy, the patient’s stem cells are reintroduced into their bodies. This re-establishes the patient’s immune system and restores the body’s ability to fight disease and produce platelets. This type of interaction is also known as a stem cell rescue or auto transplant.
2. Allogeneic Transplants
Allogeneic transplants involve taking cells from a donor to perform the procedure. The donor should be a close genetic relative of the recipient. Usually, a living relative is the best preference, but genetic matches can also be found through a donor registry.
If you have a medical condition that has damaged your bone marrow cells, allogeneic transplants are crucial. Nonetheless, they have a greater risk of developing complications, such as GVHD. In addition to this, it is quite likely that you will be required to take medications to suppress your immune system to prevent your body from attacking the newly implanted cells. Because of this, you may become susceptible to illness.
The success of an allogeneic transplant is determined by the degree to which the donor cells match the recipients.
Considerations Before a Bone Marrow Transplant in Turkey
- During your pre-medical evaluation, please inform your medical consultant about the medicines, vitamins, herbal supplements you have been using.
- Please bring all your medical results and reports with you.
Your doctor will recommend the best transplant option for you. Your options are determined by the type of infection examined, the state of your bone marrow, your age, and your overall health. If you have malignancy or another illness in your bone marrow, you will likely receive an ALLO transplant since the replacement undifferentiated organisms must come from a healthy donor.
Before receiving the new fundamental microorganisms, you may undergo radiation or chemotherapy to kill all malignant tissue or marrow cells. Your immune system will be suppressed while you are receiving treatment, which will impair its ability to protect you from illness. Thus, you will stay in a special area of the emergency clinic that is reserved only for patients receiving bone marrow transplants in Turkey.
Why is Turkey the Best Option for Receiving a Bone Marrow Transplant?
Notwithstanding their excellent success rates, Turkey’s hospitals are known for their affordable treatment options. In the past few years, medicine in Turkey has reached a world-class level thanks to the strong subsidizing of this industry and the swift implementation of American standards in clinical practice and doctor training.
The fact that Turkish hospitals have earned a variety of international accreditations, such as that granted by the Joint Commission International (JCI), sometimes known as the “Gold Standard of Medicine,” is evidence that these clinics are in line with the high standards of modern medicine.
In Turkey, bone marrow transplant is as effective as 70% of the time, and this system costs roughly half as much as its European counterparts. In addition, the average price of basic goods, as well as the cost of food and other needs, are less expensive in this country than they are in the US and the EU.
How are Bone Marrow Transplants Performed?
There are differences between the phases of an allogeneic and autologous bone marrow transplant.
In the autologous bone marrow transplant:
- Patient-specific peripheral blood stem cell collection. Before the procedure, a patient receives medications that divide undifferentiated cells and increase their peripheral blood count.
- Killing sick bone marrow. Patients get a great deal of chemotherapeutic specialists or radiation.
- Stem cell reintroduction. Through the catheter, undeveloped cells are reinfused into a patient’s circulation.
- Post-op surveillance. A clinical team monitors vital signs, anti-toxins, and possible outcomes.
In the allogeneic bone marrow transplant:
- Finding a suitable donor. HLA testing finds the best benefactor from the patient’s family or the volunteer library of random contributors.
- Donor stem cell harvesting. The peripheral blood or bone marrow may include immature germs.
- Eliminating sick bone marrow. High-dose chemotherapy may be followed by radiation.
- Redistribution of donor stem cells. The catheter implants donor undeveloped cells into a patient’s circulatory system
- Recovery and post-op monitoring. Patients who receive allogeneic fundamental microorganisms get medications to prevent GVHD.
What are the potential risks associated with Bone Marrow Transplant?
A bone marrow transplantation is considered a significant surgical procedure that increases the likelihood of experiencing:
- low blood pressure
- nausea
- headache
- fever
- shortness of breath
The foregoing adverse effects typically only last for a short period of time; nonetheless, relocating the bone marrow might create some inconvenient side effects. Your chances of creating these challenges depend on a number of different factors, including the following ones:
- your age
- your overall health
- the illness that you are being treated for
- the type of relocation that you have gotten
Recovery after bone marrow transplant in Turkey
In general, recovery period is around three months following a bone marrow transplant. Either way, it might take up to a year for you to fully heal. Recovery depends on several factors, such as:
- the condition that is being treated
- chemotherapy
- radiation
- a compatible donor
Bone Marrow Transplant Cost in Turkey
Bone Marrow Transplant in Turkey typically costs between $33.000 and $75.000. It’s important to keep in mind that these costs are estimates and that the exact amount will change based on the patient’s needs, doctor’s experience, and quality of the hospitals.